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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 54-year-old male patient (BSA = 1.8 m2) is being treated for head and neck cancer with the following regimen:
* Cisplatin 100 mg/m2 intravenously on day 1
* 5-Fluorouracil 1000 mg/m2 intravenously by continuous infusion on days 1 through 5
* Ondansetron 16 mg intravenously
Which of the following is the appropriate administration instruction for ondansetron?

A) Daily prior to 5-fluorouracil infusion on days 1 through 5
B) Thirty minutes before Cisplatin on day 1
C) Thirty minutes prior to Cisplatin, thereafter as needed for nausea
D) One dose 30 minutes before Cisplatin and a repeat dose immediately before 5- fluorouracil on day 1; then repeat daily before 5-fluorouracil

2. A patient presents at a physician's office with gait unsteadiness and clumsiness. The patient has a history of type 2 diabetes mellitus, hypertension, and chronic numbness and tingling of the feet and fingertips.
Examination reveals mild distal wasting, glove-and-stocking sensory impairment, absent ankle jerks, brisk knee jerks, and bilateral Babinski reflexes. Gait is slightly ataxic.
CBC reveals a hemoglobin of 10.1 g/dL, WBC of 4,500 cells/mL, MCV 120 fL, and platelets
163,000 cells/ul.
Which of the following is the most important laboratory test for assisting in diagnosis?

A) Ferritin
B) Folic acid
C) Serum vitamin B12
D) Erythrocyte sedimentation rate

3. Administration of a marketed drug to a patient for an off-label indication without approval from a local IRB is permissible in which of the following situations?

A) The patient's physician has filed a Notice of Claimed Investigational Exemption for a New Drug with the FDA.
B) The patient's physician considers that the risk/benefit ratio favors the use of the drug.
C) The drug is administered under a protocol sponsored by an NIH grant.
D) The drug is administered on the request of the patient or the patient's representative.

4. A 28 year old patient presents to a physician and reports persistent nasal discharge and facial tenderness for the past 15 days. The patient has no known drug allergies. Which recommendation would be best for treating this acute sinusitis?

A) Amoxicillin/clavulanate acid
B) Sulfamethoxazole/trimethoprim
C) No antimicrobial indicated at this time
D) Azithromycin

5. A 58-year-old man presents with symptoms of the common cold (nasal congestion, headaches, and dry Cough).
He purchased XYZ Cold formula (acetaminophen, pseudoephedrine, and dextromethorphan), but after reading the cautionary information on the package, he thought he should obtain his pharmacist's advice. He has hypertension and is taking hydrochlorothiazide daily. His office blood pressures range from 127-134/82-88 mm Hg, and he has no other medical problems.
Which of the following instructions are applicable to this patient regarding XYZ Cold formula?

A) Although pseudoephedrine is safe to use, he should use an antihistamine instead to better control his symptoms.
B) He should avoid XYZ Cold because it significantly raises blood pressure.
C) He should substitute nasal cromolyn for the decongestant.
D) XYZ Cold would be safe short term because he has well-controlled hypertension.

Solutions: