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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. In this case, with the pre-incubation aPTT mixing study result "corrected" and the post-incubation aPTT mixing study result "not corrected", a coagulation inhibitor should be suspected. Both anti-factor VIII and lupus anticoagulant have been known to be slow-acting and can exhibit this result pattern. If a factor deficiency was present, we should not see a post-incubation prolongation.
Hematology
What may cause the following mixing studies results?
Initial aPTT = 133 seconds
1:1 Mix aPTT pre-incubation = 33 seconds
1:1 Mix aPTT post-incubation = 124 seconds

A) Factor IX deficiency
B) A slow acting coagulation inhibitor
C) Factor XI deficiency

2. VLDL transports endogenous lipids, whereas chylomicrons transport exogenous (dietary) lipids. Cholesterol is transported by HDL and LDL.
The function of the very low density lipoproteins (VLDL) is to transport:

A) cholesterol from peripheral cells to the liver
B) endogenous triglycerides
C) cholesterol and phospholipids to the peripheral cells
D) exogenous triglycerides

3. Which specimen should be collected last?
Question options:

A) Fasting specimen
B) STAT specimen
C) Specimen requiring special handling
D) Clotted specimen

4. Nucleated RBCs may be seen in the peripheral blood in cases of beta thalassemia major. Nucleated RBCs are usually not found in peripheral blood in cases of beta thalassemia minor and beta thalassemia intermedia, and would not be a finding in beta thalassemia minima.
Nucleated RBCs are most likely to be seen in the peripheral blood of which of these beta thalassemias?

A) Beta thalassemia minor
B) Beta thalassemia minima
C) Beta thalassemia major
D) Beta thalassemia intermedia

5. Skeletal deformations result from the increased erythropoiesis that occurs in beta thalassemia major. Children with beta thalassemia intermedia may demonstrate some facial bone deformity, however this is not common.
Beta thalassemia minor rarely causes any physical signs or symptoms and beta thalassemia minima is completely asymptomatic.
Skeletal deformations are most commonly present in which of the following beta thalassemias?

A) None of the beta thalassemias
B) All of the beta thalassemias equally
C) Beta thalassemia minor
D) Beta thalassemia major
E) Beta thalassemia intermedia

Solutions: